President Trump says US Navy will begin blockade of Strait of Hormuz

President Donald Trump issued a broad threat against Iran on Tuesday morning, as his Tuesday evening deadline loomed for Tehran to fully reopen of the Strait of Hormuz.

"A whole civilization will die tonight never to be brought back again. I don't want that to happen, but it probably will," Trump wrote on his social media platform. It was not immediately clear what the president was referring to. Trump has repeatedly threatened punitive strikes against critical Iranian infrastructure.

"However, now that we have Complete and Total Regime Change, where different, smarter, and less radicalized minds prevail, maybe something revolutionarily wonderful can happen, WHO KNOWS?" Trump also wrote.

"We will find out tonight, one of the most important moments in the long and complex history of the World. 47 years of extortion, corruption, and death, will finally end. God Bless the Great People of Iran!" the president said.

The United States struck military targets on Kharg Island overnight, according to a U.S. official.

These strikes targeted some of the same military targets struck in the earlier strike in March, though the official stressed that these strikes did not target the island’s oil infrastructure.

-ABC News' Luis Martinez

A synagogue in Tehran was "completely destroyed" in U.S.-Israeli strikes overnight, the official Islamic Republic News Agency reported on Tuesday.

Located in central Tehran, Rafi-Nia Synagogue served as a religious center for the city's Jewish community, the semi-official ISNA News Agency reported.

The attacks were condemned by Homayoun Sameh Najafabadi, the representative of the Jewish community in Iran's parliament, according to IRNA. He said that carrying out the strikes during the Passover holiday showed that Israel had an "anti-religious attitude."

"At the beginning of the attack on our country, Trump claimed that he was carrying out these strikes in support of the people. But later, most of those who were martyred, injured, or disabled by the United States and Israel were these same people," Najafabadi said.

-ABC News' Somayeh Malekian

The Israel Defense Forces said in a post to X on Tuesday that it "completed a wide-scale wave of strikes targeting dozens of infrastructure sites" in several areas of Iran.