No one was injured, according to the Qatari Ministry of Defense.
President Donald Trump announced "major combat operations" against Iran on Saturday, with daytime strikes in the joint U.S.-Israel attack targeting military and government sites, officials said.
On Sunday, Iranian state television confirmed that Ayatollah Ali Khamenei was among those killed by airstrikes in Tehran on Saturday.
Iran is responding to the U.S.-Israeli operation with missile and drone attacks targeting Israel, regional U.S. bases and Gulf nations. American diplomatic facilities have also been attacked.
In Lebanon, Israel is intensifying its long-running strike campaign against the Iranian-aligned Hezbollah militia.
Watch special coverage on Nightline, "War with Iran," each night on ABC and streaming on Disney+ and Hulu.
The Iranian Red Crescent Society said Tuesday that at least 787 people had been killed by U.S.-Israeli strikes in Iran since Saturday, according to the semiofficial ISNA news agency.
-ABC News’ Somayeh Malekian and Morgan Winsor
The U.S. Embassy in Riyadh said in a statement that it will be closed on Tuesday following an attack on the facility by Iranian drone strikes overnight.
The embassy said in an update that a shelter-in-place order remained in effect for Jeddah, Riyadh and Dhahran. It urged Americans throughout Saudi Arabia to stay inside.
Tens of thousands of Americans live in Saudi Arabia, according to recent estimates.
-ABC News' Marcus Moore, Dada Jovanovic and Colm O'Molloy
Israeli Defense Minister Israel Katz said in a post to X on Tuesday that the "combined Israeli-American attack on Iran" is intended -- in part -- to "create the conditions for the Iranian people to act and remove" the government in Tehran.
"We have severed the head of the Iranian octopus and we are now working to crush and sever the octopus's tentacles," Katz wrote.
The Israeli-U.S. campaign, he said, "is unprecedented in its scope, precision, and power -- and it aims to crush the regime's capabilities, protect Israel's home front and U.S. military forces in the region, prevent Iran from returning to the path of nuclear weapons production and mass missile production," and help Iranians topple the regime.
The operation, Katz said, "will continue with full force for as long as required."
U.S. Central Command -- CENTCOM -- said in a post to X on Tuesday morning that it had "destroyed Islamic Revolutionary Guard Corps command and control facilities, Iranian air defense capabilities, missile and drone launch sites and military airfields."
"We will continue to take decisive action against imminent threats posed by the Iranian regime," CENTCOM added.
