Two C-130 aircraft were lost during the operation, an official said.
President Donald Trump announced "major combat operations" against Iran on Feb. 28, with massive joint U.S.-Israeli strikes attack targeting military and government sites, officials said.
Watch special coverage on Nightline, "War with Iran," each night on ABC and streaming on Disney+ and Hulu.
At least eight civilians were killed and 95 others were injured in the U.S.-Israeli attack on the B1 bridge between Karaj and Tehran on Thursday, according to Iran's semiofficial Fars News Agency, which is affiliated with the Islamic Revolutionary Guard Corps.
ABC News can not independently confirm the deaths.
President Donald Trump said that Iran is "eager" to make a deal and revealed that the U.S. "blew up their three big bridges last night," in an interview with TIME Magazine Thursday.
"Why wouldn't they call? We just blew up their three big bridges last night," the President said. "They’re getting decimated. They say Trump is not negotiating with Iran. I mean, it's sort of an easy negotiation."
When pressed about whether Israel would stop when the U.S. stops the war, Trump said that they will "stop when [he stops]," but added that they would stop unless "they're provoked."
“They'll do what I tell them. They've been a good team player. They'll stop when I stop. They'll stop unless they're provoked, in which case, they'll have no choice, but they'll stop when I stop," Trump said about the Israelis, according to Time.
Iran claimed its IRGC Nacy Command targeted the data centers of two major American companies in the region -- Oracle in Dubai and Amazon in Bahrain -- according to Iran's semiofficial Fars News Agency.
Israel claims to have targeted and killed a regional commander from one of Iran's ballistic missile units, according to a statement from the Israeli Defense Forces.
"In a precise strike in the Kermanshah area, the Israeli Air Force struck and eliminated Makram Atimi, the Commander of a central missile unit in western Iran," the statement from the IDF said.
Israel said it would continue to eliminate commanders of Iran's ballistic missile array.
"Atimi was responsible for the unit’s operations in the Kermanshah region in western Iran and carried out dozens of ballistic missile launches toward the State of Israel," the IDF said.
Iran has not confirmed Atimi's death.
