Russia-Ukraine updates: Russian missiles hit close to nuclear reactors: IAEA director

Russia's recent missile strike on a shopping mall in the central Ukrainian city of Kremenchuk, which killed at least 20 people, may have been "intended to hit a nearby infrastructure target," the U.K. Ministry of Defense said Wednesday in an intelligence update.

The ministry called it "a realistic possibility" and noted that "Russia's inaccuracy in conducting long range strikes has previously resulted in mass civilian casualty incidents, including at Kramatorsk railway station" on April 9.

"Russian planners highly likely remain willing to accept a high level of collateral damage when they perceive military necessity in striking a target," the ministry said. "It is almost certain that Russia will continue to conduct strikes in an effort to interdict the resupplying of Ukrainian frontline forces."

"Russia's shortage of more modern precision strike weapons and the professional shortcomings of their targeting planners will highly likely result in further civilian casualties," the ministry warned.

Twenty people are dead and 59 are wounded from Russia's missile strike on Monday at a mall in the central Ukrainian city of Kremenchuk, according to Kyrilo Tymoshenko, the deputy head of the Office of the President of Ukraine.

Forty people remain missing, Tymoshenko said.

"Several fragments of bodies have been found ripped off limbs and feet of the people," Ukrainian President Volodymyr Zelenskyy told the United Nations Security Council.

He said if Russia denies the devastation was wrought by one of its missiles, he asked the U.N. send an independent representative to the site of the attack to verify for itself.

First Deputy Permanent Representative of Russia to the U.N., Dmitry Polyanskiy, flatly denied carrying out strikes against any civilian target.

-ABC News' Shannon Crawford, Oleksii Pshemysko and Fidel Pavlenko

Sean Penn met with Ukrainian President Volodymyr Zelenskyy in Kyiv on Tuesday after the actor arrived in Ukraine to shoot a documentary, according to Zelenskyy’s office.

Penn, who first came to Ukraine on the day Russia invaded in February, wants to "visit settlements in Ukraine affected by Russian aggression," according to Zelenskyy’s office.

President Joe Biden and Spanish President Pedro Sanchez delivered remarks Tuesday on new areas of cooperation between the two countries and efforts to keep supporting Ukraine against Russia's invasion.

Biden did not mention Monday’s strike on the Ukraine mall that killed 18, but said the invasion has "shattered peace in Europe and every norm since WWII."

Biden said he and Sanchez discussed the need to continue to provide weapons to Ukraine.

The Ukrainians "are standing up in ways that I don't think anyone anticipated, showing enormous bravery, enormous resolve," Biden said.

He said he believes Putin's objective is to "wipe out the culture of Ukraine."

Biden said NATO allies will be "standing as one" to support Ukraine and teased more military posture commitments in Europe. Biden said the U.S. and Spain are working on an agreement to increase the number of Navy destroyers stationed at Rota Naval Base in Spain.

-ABC News' Justin Ryan Gomez